Myeloproliferative and Myelodysplastic Disorders
Myeloproliferative and myelodysplastic disorders are hematologic conditions characterized by abnormal proliferation or ineffective production of blood cells. Myeloproliferative disorders include polycythemia vera, essential thrombocythemia, and primary myelofibrosis, while myelodysplastic syndromes involve defective hematopoiesis leading to cytopenias and potential progression to leukemia. Biologically, these disorders arise from mutations in hematopoietic stem and progenitor cells, affecting proliferation, differentiation, and apoptosis. Diagnostic methods include complete blood counts, peripheral blood smears, bone marrow biopsy, cytogenetic analysis, flow cytometry, and molecular testing for mutations such as JAK2, CALR, or MPL. Laboratory instruments include automated analyzers, flow cytometers, sequencing platforms, and microscopes. Management strategies involve targeted therapies, cytoreductive treatment, supportive care, and hematopoietic stem cell transplantation. This session provides delegates with an in-depth understanding of the biological mechanisms, diagnostic methods, instrumentation, and therapeutic approaches for myeloproliferative and myelodysplastic disorders.
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Myeloproliferative and Myelodysplastic Disorders Conference Speakers
Recommended Sessions
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