Gene Therapy and Genetic Engineering
Gene therapy and genetic engineering are rapidly advancing fields in hematology, offering potential cures for inherited and acquired blood disorders. Biologically, these approaches involve correcting or modifying defective genes responsible for conditions such as sickle cell disease, thalassemia, hemophilia, and immunodeficiencies. Techniques include viral vector-mediated gene delivery, CRISPR-Cas9-based gene editing, and RNA-based therapies, which enable targeted modifications of hematopoietic stem cells or immune cells. Diagnostic and laboratory methods are essential for patient selection, monitoring, and evaluating therapy efficacy. These include molecular genetic testing, sequencing, flow cytometry, PCR assays, and functional studies to assess gene expression and protein production. Instruments such as gene-editing platforms, automated cell culture systems, flow cytometers, PCR machines, and high-throughput sequencing instruments support research and clinical applications. Gene therapy allows personalized treatment by restoring normal gene function, improving hemoglobin production, or enhancing immune function. Clinical outcomes have shown remarkable improvements in patients previously dependent on lifelong transfusions or therapies. Safety monitoring is critical, as off-target effects, immune reactions, and vector-related complications must be managed. This session provides delegates with an in-depth understanding of the biological basis, laboratory techniques, instrumentation, and clinical applications of gene therapy and genetic engineering, emphasizing the transformative potential of these approaches in modern hematology.
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Gene Therapy and Genetic Engineering Conference Speakers
Recommended Sessions
- Advances in Hematology Research and Clinical Trials
- Blood Disorder Diagnostics and Biomarkers
- Blood Transfusion and Immunohematology
- Clinical Research, Case Studies, and Translational Hematology
- Coagulation and Hemostasis Disorders
- Emerging Therapies and Precision Medicine in Hematology
- Gene Therapy and Genetic Engineering
- Hematologic Malignancies
- Hematology Imaging and Laboratory Technologies
- Hematology in Infectious Diseases
- Hemoglobinopathies and Genetic Blood Disorders
- Hemostasis and Thrombosis Research
- Immunotherapy in Hematology
- Iron and Nutritional Anemias
- Myeloproliferative and Myelodysplastic Disorders
- Pediatric Hematology
- Platelet Disorders and Thrombocytopenia
- Rare and Autoimmune Blood Disorders
- Stem Cell and Bone Marrow Transplantation
- Transfusion-Related Complications and Safety
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